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A multicenter randomized trial of computer-driven protocolized weaning from mechanical ventilation

Authors
Lellouche, F., Mancebo, J., Jolliet, P., Roeseler, J., Schortgen, F., Dojat, M., Cabello, B., Bouadma, L., Rodriguez, P., Maggiore, S., Reynaert, M., Mersmann, S., Brochard, L.
Journal
Am J Respir Crit Care Med
Publication Date
2006 Oct 15
Volume
174
Issue
8
Pages
894-900
  • HIT Description: Decision support More info...
  • Purpose of Study: to determine whether an automated, continuous, protocol-driven ventilation and weaning process is more successful than usual care in assessing patient readiness for weaning
  • Years of study: 2002-2003
  • Study Design: RCT
  • Outcomes: impact on health care effectiveness and quality; impact on efficiency, utilization and costs
Summary:
  • Settings: Medical-surgical ICU patients from 5 teaching hospitals in Spain, Belgium, France, and Switzerland
  • Intervention: patients in the intervention group were on ventilators equipped with the system to assist in weaning while control patients were weaned based on usual local practice with guidelines available in 4 units
  • Evaluation Method: not described, presumably chart review
  • Description: closed-loop, knowledge-based system embedded in a standard ventilator that adapts the level of pressure support to continuously recorded data on the patient's needs and comfort and automatically tries to wean the patient
  • Quality of Care and Patient Safety Outcome: Wean time was greatly reduced with the computer-driven weaning (2 days vs 4 days);
  • Changes in efficiency and productivity: Total duration of mechanical ventilation and ICU length of stay were also reduced.
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