Computer-assisted medication review for asthmatic patients as a basis for intervention. Constructing and validating an algorithmic computer instrument in pharmacy practice
Journal
Pharm World Sci
Publication Date
2004 Oct
Volume
26
Issue
5
Pages
289-96
Summary:
- HIT Description: algorithmic computerized instrument to detect asthma patients with suboptimal pulmonary drug use More info...
- Purpose of Study: to construct an instrument to detect non-adherent behavior in asthma patients and validate the selection profiles of the instrument
- Years of study: 1998
- Study Design: other predictive analysis
- Outcomes: impact on healthcare effectiveness and quality
- Settings: Dutch asthma patients between ages 13 and 40 who received four or more prescriptions for pulmonary drugs in one year from 4 pharmacies
- Intervention: algorithmic computer instrument was constructed by manually identifying patients not using optimal levels of drugs (defined by Òdefined daily dosesÓ) and stratifying them into 9 different selection profiles. The instrument was then used to separately identify patients with deviant drug use and this list was compared to the original manual list
- Evaluation Method: InterAction database (Dutch national pharmacy database)
- Description: constructed by conducting searches of the InterAction pharmacy database using changing combinations and amounts of drugs in order to select the same patients that were identified manually by a pharmacist for inappropriate drug use. Selection profiles were then developed.
- Quality of Care and Patient Safety Outcome: The positive predictive and negative predictive values of the computer instrument were 95% with a rate of false positive identification of 5%